Subcutaneous calcinosis in systemic sclerosis

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MDCT imaging of calcinosis in systemic sclerosis.

Calcinosis is a typical feature of systemic sclerosis (SSc) and can be found in many different tissues including the superficial soft tissues, periarticular structures, muscles, and tendons. It can also provoke erosive changes on bones. Investigation is conducted most often with plain radiographs. However, when a more detailed assessment is necessary, multidetector computed tomography (MDCT) is...

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Severe Calcinosis in Limited Cutaneous Systemic Sclerosis

A 56-year-old woman presented with long-standing pain in both knees. She had been suffering from Raynaud’s phenomenon for 10 years. A physical examination showed hard subcutaneous nodules on the extensor surfaces of both knees and elbows (Picture 1: left elbow and right knee) with sclerodactyly and telangieclagia in both hands. The Creactive protein level was normal (0.08 mg/dL, normal < 0.3), ...

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Clinical significance of subcutaneous calcinosis in patients with systemic sclerosis. Does diltiazem induce its regression?

OBJECTIVE To establish whether diltiazem reduces subcutaneous calcinosis (SCC) in patients with systemic sclerosis (SSc), and whether this calcinosis is related to other signs or symptoms. METHODS 47 patients with SSc were evaluated and divided into two groups according to the presence or absence of SCC. RESULTS Among the 12 patients with SCC who were treated with diltiazem and had sequenti...

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Cervical and lumbar paraspinal calcinosis in systemic sclerosis.

Calcinosis is a well-recognized manifestation of systemic sclerosis. Paraspinal or intraspinal calcinosis is rare, with reports of calcinosis involving the cervical, thoracic and lumbar separately, but not together. We now report a case of limited cutaneous scleroderma with extensive paraspinal calcinosis of the cervical and lumbar spine.

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A case of a generalized symptomatic calcinosis in systemic sclerosis.

Calcinosis consists of abnormal calcium deposition in soft tissues, which appears often in patients with limited systemic sclerosis, being one of the criteria of CREST (calcinosis cutis, Raynaud phenomenon, esophageal dysfunction, sclerodactyly, and telangiectasia) syndrome. With a long evolution, the aim of the treatment is to control the symptoms and prevent complications. In this article, we...

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ژورنال

عنوان ژورنال: Arthritis & Rheumatism

سال: 1996

ISSN: 0004-3591,1529-0131

DOI: 10.1002/art.1780390512